On-Campus Research Biochemistry Environmental Inorganic Organic Physical  Off-Campus

On-Campus Research Opportunities

     Rice's chemistry department strongly supports undergraduate research. All chemistry majors are required to take at least 3 credit hours of research (CHEM 491), but any motivated student, any year, any major is always welcome. And you won't just be washing glassware. Professors realize the value of undergraduates and allow them to participate in actual, ground-breaking research. An incredible number of papers have been co-authored (and even authored) by Rice undergraduates, not to mention the posters and presentations given at local or national meetings. Whether you just finished struggling through freshman chemistry or you're a senior who has worked at Harvard for the past 3 summers, there are professors who are willing to work with you.

     You can either get paid or get credit for research (not both). Most people get credit during the school year and get paid over the summer. The major drawback to research is that it can be very time consuming, so we don't recommend trying it during really hard semesters.

     Take a look at the descriptions, but don't stop here. Email or stop by the professors' offices to talk about their research in more detail and see if they have space available. The professors are approachable and you will learn a lot by talking to them.

 

Brought to you by Owlchemy (Student Affiliates of the American Chemical Society)
Please send comments to owlchemy@rice.edu

All pictures of the professors on these research pages are courtesy of dacnet.rice.edu.

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Andrew R. Barron

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Research Projects: Chemistry and Materials Science of the Group III (13) metals

1. Aluminum-oxide nano-particles as new materials and precursors for ceramics with controlled porosity.
2. Group 12/13 catalysts for H/D exchange and olefin oligomerization.
3. The chemistry of borate and aluminates in the oil industry.
4. Alumoxane catalysts.

Your Job in the Lab: The students are given their own project to work on.

Recommended experience: The student should have already taken undergraduate chemistry labs (i.e. CHEM 121-122 (general chemistry labs), 213-214 (the organic chemistry labs), or the module system).

Positions Open: There is currently 1 position for the summer and 1 position for the fall of 2000.  Students may continue working through the year if they come in during the summer.

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Bonnie Bartel

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What you would do: This project will be available starting in January to analyze a plant mutant that has increased sensitivity to the phytohormone auxin.  The project involves phenotypic characterization and recombination mapping using PCR-based molecular markers.  This would be appropriate for a BIOS 310 student.
Suggested experience:  I am looking for someone who is interested in genetics, and who is interested in the possibility of continuing the project through the summer (and possibly next year as well).  A sophomore would be my first choice; juniors and freshmen are also possibilities.

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Kate Beckingham 

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What would you do: This lab will studying Gravitoxic Drosophila (fruit fly) mutants.

Positions Open: I need 4-5 undergrads next semester.  If you are interested email her ASAP at kate@bioc.rice.edu.

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Victor Behar

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This group does "traditional organic synthesis." They don't have a homepage yet, but they should soon.

Synthetic organic chemistry and methodology development. Synthesis of bioactive natural products. Synthesis of optically active biaryls for use in catalytic enantioselective synthesis.

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W. Edward Billups

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Hydrocarbon Chemistry- theoretically interesting molecules.

Chemistry of small ring systems; reactive intermediates; synthetic methods; organo-transition metal chemistry, chemistry of free metal atoms; fullerene chemistry.

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Janet Braam

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What would you do:Molecular genetic techniques are used to elucidate the functions of genes involved in plant cell signaling and wall genesis. We are interested in how these genes are used to help plants adapt to environmental stress.

Organization: Most undergraduate students have relatively independent research projects or may work closely with a graduate student or postdoc.  Some students who have little or no experience may start by helping to prepare reagents, pour plates, do DNA preparations, etc.
Positions Open: I usually have at least two positions for undergraduate researchers in my lab.

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Phillip R. Brooks

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What you would do:This group is studying electron transfer by detecting the positive and negative ion formed when two neutral species collide.  You could make measurements to determine the energy of the collision . Alternatively, you could write computer code for developing new coincidence methods for making measurements of the initial and final energy.
What you would learn: You would be exposed to a wide variety of experimental skills, such as design and construction of mechanical and/or electronic apparatus, computer interfacing, and data analysis.  There might be opportunities to gain experience in Fortran and/or Matlab.
Organization: The professor works in the lab and is available for discussion, but students are allowed to work by themselves.
Suggested Experience: Experience in mechanical and/or electrical work would be useful for an experimentalist.  Interest or experience in computer programming is a necessity for someone writing code.  Anyone who is interested will be considered, but should probably have completed freshman-level courses.

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Vicki L. Colvin

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Description: We both make (synthesis) and study (physical chemistry) nanoscale materials. Some of the nanosized systems we look at are interesting for their potential technological relevance: artificial opals, for example, are great optics which allow for precise control over the propagation of light.  We have a large effort in making opals, and in using them as scaffolds to construct new porous materials.  Other projects are motivated by fundamental questions which seek to elucidate the difference between "molecules" and "solids".  We can address this issue because we can make molecules of increasingly larger size- and study how molecular properties evolve into bulk solid state behavior.  Our web page at nanonet.rice.edu has a current list of all of these diverse research areas and their current status.

Your Job in the Lab: It will depend on the student's interests.  We have found that our group, as well as the students who
work with us, benefit the most when undergraduate project's  are defined by what they need from the experience rather than what work we need done. Sometimes, undergraduates are certain they want to go to graduate school in chemistry.  In this case, their undergraduate research is critical to their future career so we encourage them to start work early with us and steer them onto projects that are producing publications in the near-term.  Often undergraduate students interested in graduate school are not certain about the specific area (inorganic, organic, physical, theory) they want to specialize in.  Given the diversity of work in our group, we can provide these "undecided" people with a broad experience, in both synthesis and physical measurement, so they can evaluate what area they like the best.  Finally, in some cases students have non-research career plans and only work in our group briefly. In this instance, we find that it is best to have them work as part of a larger team (more than 3 student) project so they learn about the many different aspects of a research environment in their short time.

Recommended experience: If a student is interested in a brief, semester-long, project we prefer seniors who have had several advanced labs, as well as physical chemistry.  However, if a student wants to start early and stay working in our group for a while, we are willing to train them in the laboratory and instrumentation skills necessary for our projects.

Positions Open: We typically have 3-4 summer and semester undergraduate research positions. This year the potential projects include an instrumental project which would be learning scanning electron microscopy to look at nanoscale materials, a biological materials project which is a collaborative effort with biochemistry, and an experimental/theory project on opals

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Robert F. Curl

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Description: We investigate the gas phase infrared spectra and chemical kinetics of small highly reactive free radical species. Mostly  we are interested in radicals which may play some role in combustion. We produce these radicals by flash photolysis of a suitable precursor and probe their infrared absorption spectra with single frequency, cw, tunable IR lasers. We are also working on observing larger free radicals by IR at the very low temperatures achieved by supersonic expansion. We also are developing infrared laser IR atmospheric monitors.
Your Job in the Lab: Organic synthesis of precursor compounds that are photolyzed to produce free radicals. Once you make the compound, you can see what happens when it is photolyzed,  working with other members of the research group. Or, you can do computer programming. concerned with improving our data collection and data analysis software.
Recommended Experience: For synthesis the basic introductory modules 351 and 352 although the advanced module in synthetic chemistry 372 would be desirable. For programming a knowledge of Quickbasic for the PC is needed and some knowledge of PC assembly language is desirable.
Positions Open: Probably 1 perhaps 2 positions will be available in the summer and fall of 2000.

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Paul S. Engel

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What you would do: Short synthesis of an unnatural product, something that is needed for mechanism studies.  Alternately, you might do first order kinetics on a compound that you or somebody else has made.
What you would learn:The techniques used for kinetics are usually UV, NMR, or gas evolution. You can learn a  huge amount amount about laboratory technique, spectral interpretation, and operation of analytical instruments. Publication is possible  for students who work more than one semester.
Organization: Supervised by a postdoc, with periodic discussions with professor when you wish.
Suggested Experience: Elementary organic chemistry is a must. Advanced orgo and Chem 352 are helpful.

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Sue Gibson

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What you would do: This will be for a paid lab assistant to do dishes, autoclaving and help with experiments.
Positions Open: I will probably have one position available next semester. A work-study student would be preferred.
Environment: This lab will require about 10-15 hours/week.

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Raymon Glantz

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What you would do: In this lab, you would study neurotransmitter biding to neural receptors.
Positions Open: I may have a position this spring.
Environment: This lab will require about 12 hours/week.

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Graham P. Glass

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We study molecules and reactions involved in combustion processes such as those occuring in an acetylene flame. In particular, we observe highly reactive, short-lived species called "radicals" that are difficult to track using conventional methods. With our equipment, we can create radicals through photolysis (the breaking up of a molecule using light) of stable molecules. We can then monitor the infrared spectra of the radical in order to determine information about its structure, or we can monitor its reaction over time with itself or other molecules in order to determine its rate of reaction.

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Richard Gomer

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Positions Open: I always have (unpaid) research projects for undergrads.
Note: Typically students contact me, we talk about what they are interested in doing and how much time they have for the project, and we find something.

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Naomi J. Halas

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Description: The Halas Nanoengineering Group explores the synthesis, properties, and "technology" of nanoscale particles. In the past few years, we have developed a new type of nanoparticle called a Nanoshell, which is a spherical, layered nanoscale structure consisting of a dielectric core (silica) coated by a thin metal shell (gold or silver, for example). By adjusting the relative diameter of the core and thickness of the shell we can tune the optical absorption of Nanoshells over an enormous wavelength range, from the visible to the infrared: this far-ranging optical tunability is unique to Nanoshells. We have also developed a new method of synthesizing silica nanoparticles doped with lanthanide ions, which have enormous potential for use in optical devices, and we have recently developed new methods for synthesizing novel anisotropic nanoparticles. The Halas group webpage is found at http://www.ece.rice.edu/~halas.
Atmosphere: Our group is the most multidisiplinary research group on campus with members and alumni from Physics, Applied Physics, Physical, Inorganic, and Organic Chemistry, Electrical Engineering, Chemical Engineering, Materials Science, and Bioengineering. The group atmosphere is very friendly, cooperative, and motivated. There is a strong emphasis on individual professional development, where all participants develop a broad range of skills, learn, make mistakes, and celebrate achievements. Each group member (including undergraduates) works on his or her own separate research project, but communication and collaboration between group members frequently occurs. Undergraduates would be guided by a graduate student or students, but would most likely be pursuing their own project goals.
Undergraduate Opportunities: Currently we have projects ranging from the basic physics and chemistry of our nanostructures to the development of various technological applications utilizing our nanostructures. We have projects open to undergraduates ranging from synthetic chemistry to physics to computer science. Among these are the synthesis of nanoshells of different metals, different cores, and with dopant species inside, assembly of nanostructure aggregates, studies of the Surface Enhanced Raman Scattering effects from nanoshells, an NMR project to study the relaxation of water molecules around various types of nanoparticles, or a theory project which would examine the changes in electromagnetic responses of anisotropic nanoparticles and self-assembled nanoparticle aggregates. There is also the opportunity to work on polymer chemistry projects investigating the chemical modification of hydrogel/nanoshell composites. (These composite materials are useful for photothermally-triggered drug delivery and were developed through our long-term collaboration with Prof. Jennifer West's group in Bioengineering.) You will have the opportunity to learn a variety of instrumental techniques such as scanning electron microscopy, transmission electron microscopy, atomic force microscopy, as well as a broad range of spectroscopies (UV-vis, IR, Raman).
Recommended Experience: We can accept seniors looking for a research project, as well as well prepared and highly motivated sophomores and juniors who would want to participate in our research group as a long-term research experience.
Positions Open: We can accommodate 2-3 undergraduates.

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Robert H. Hauge

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CVD Diamond Growth Mechanisms, Reactions of Metal Atoms and Small Clusters, Measurements of the Physical and Thermodynamic Properties of Liquid Metals and Alloys.

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John S. Hutchinson

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What you would do: Theoretical research involving computer modelling of protien folding or energy transfer.
What you would learn:You get to work on something that's never been done before, and gain  a good understanding of your project. Dr. Hutchinson and the post-doc Sue are enjoyable to work for.
Environment:The lab is casual and friendly, but there is little interaction between group membrs, since everyone works alone at a computer.You set your own hours (typically 6-8/wk) and can log in and work from the colleges, if you want. The only drawback in this lab is that sitting at a computer too long can (literally) be a pain in the neck.
Suggested experience: Familiarity with MATLAB and UNIX (MATH211 and NSCI 230 are good preparation). Differential equations and occasionally vector are used, but mostly the math involves algebra.

What you would do: We are using laser light to study the fundamental forces that bind molecules together.  Photons scatter inelastically from the target species and transfer some of their energy, causing it to vibrate.  A new direction is a project to determine the binding forces of molecules adherent to the surfaces of small particles.  You would work on the construction of the cells that will contain the sample and the optical system that will collect and analyze the scattered light.  Subequently, you will participate in the computer controlled data collection using high-sensitivity optical detectors.  Test systems presently under consideration are ozone adsorbed onto silica particles and also halogens or amines adsorbed on graphitic carbon and C60.  This will be extended to other nanoparticles, metallic or semiconductor, as results dictate.
What you would learn: This is an excellent opportunity to add new lab skills. Specific skills are generally learned "on the job" and include vacuum systems, gas handling, optical alignment, assembling electronic circuits, and CAD design/drawing.
Organization: The undergraduate is given one or more projects which are sub-components of the larger research project.  Depending on the level of previous experience, the size of the first project is tailored accordingly.  The work is guided by a full-time experimental research scientist.  The student will carry overall responsibility to make the project work, but will have all the assistance necessary to bring it to fruition.
Suggested experience: Prior laboratory work is beneficial.
Note: This is primarily an opportunity for hands-on experimental research.  Perhaps due to the ubiquitous presence of computers, the basic experience with, e.g., mechanical and electrical devices is diminishing; yet the challenges of cutting edge scientific research requires construction of ever more sophisticated and delicate instruments.  The learning curve for acquisition of practical skills is consequently becoming steeper for successful experimental research in graduate school.  A proven track record for an undergraduate in a research lab stands out on an application.  Reports from those in our group who have gone to graduate school indicate that the undergraduate research experience has been quite beneficial in launching their graduate research program.

More information will soon follow.  Dr. Kolomeisky is currently looking for one or two undergraduates to work for him.  See his group webpage for more information.

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John L. Margrave

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Diamond Films, Levitation Studies, Environmental Chemistry, Matrix-Isolation Studies, Fluorine Chemistry

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Seiichi P.T. Matsuda

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What you would do:  This lab is composed of people from many different backgrounds, and does a
very broad range of research (ranging from evolution studies to yeast genetics to bioengineering), and it is consequently difficult to say anything specific about what sort of projects new people might pursue in this lab.  Most undergraduate students work on cloning new biosynthetic genes or generating mutants in known genes to make enzymes with new functions.
Organization: Students initially work closely with a graduate student, and then become independent
as they become more experienced.
Suggested experience:  I would rather take students as freshmen or sophomores, and have them
work with me for several years than take more advanced students and have them work for a semester or two.  I do not expect incoming students to have any specific courses or lab experience, but they must be motivated and organized so as to come up to speed quickly.
Note: This lab is an appropriate place for people interested in graduate school in the biological end of chemistry or the chemical end of biology.  We are not doing anything directly medical, and premedical students would probably be better served by finding research opportunities in the medical area.

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Ronald J. Parry

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This group is concerned with the biosynthesis of natural products and the mechanisms of enzymatic reactions. The current trend in these studies places an emphasis on the characterization of interesting biosynthetic reactions at the enzymatic level and on the application of molecular biology to the study of secondary metabolism.

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George Phillips

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What you would do: As for projects, they change all the time and I try to match a project to a student's interests.
Positions Open: I will usually take up to 2 undergraduates at a time, but no more.
Organization: I routinely have undergraduates doing research in my laboratory.  There is even a summer program in computational biology.  It seems best when students spend two semesters on a project as it takes a while to get started.  You may also know that the biochemistry and Cell Biology department encourages senior research for students with a B average or better.  I have had many of these students.

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Ronald L. Sass

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An area of current interest is a study of the biogenic emission of radiatively active atmospheric trace gases, particularly methane and nitrous oxide.

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Gustavo E. Scuseria

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What you would do: Carry out quantum chemical calculations on molecular systems and/or write computer programs in FORTRAN or C for specific methodological developments in quantum chemistry.
What you would learn: Students are expected to write papers for publication in peer-reviewed journals. You will also have a chance to experience
how this lab does theoretical chemistry (challengeing and fun). Most students in this group have been admitted to their first choice graduate school. Three have been top author on papers in top journals like Science and Nature.
Organization: Undergrads are watched loosely, but the professor's office is always open and he's usually there 8 to 6.
Suggested experience: It's best to have some Physical Chemistry and computer experience, although certain projects (like fullerenes and nanotubes) do not require it.

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Scott F. Singleton

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What you would do: Research efforts in this laboratory are divided into two project areas: Probing molecular interactions during DNA strand exchange mediated by the RecA  protein of Escherichia coli and design of modular proteins that mimic the properties of natural enzymes.
What you would learn: Strong emphasis is placed on understanding what you are doing and why it is important.
Environment:  Laid back, and easy.  Not too hard-core.  The professor is motivating, although he is often difficult to find.  The other people do not push you to challenge yourself. You typically work 10-20 hours/week.
Suggested Experience:Both semesters of orgo (Chem 211 and 212). If interested in biochemistry, Bios 301and 302 are recommended.

What you would do: Our group has two main thrusts: one is to find and develop routes for the economic bulk synthesis of carbon nanotubes, which have tremendously attractive material properties for all sorts of applications. The other is to work towards many of these applications by developing and elaborating the chemistry of short  nanotube pieces, to assemble them into functional nanostructures.
What you would learn: Multidiscplinary research in an exciting field. Most undergraduates earn authorship, many in high profile journals such as Science and Nature. You can apply principles you've learned in classes, and work towards making a profound impact.
Organization: Work closely with post docs and grad students, with significant interaction with the professors.
Environment:Intense. The professors are always eager to answer questions, but often busy.  Overall, it's a fun environment for undergrads but requires assertiveness and initiative.Dr. Smalley is understanding about other student pressures. On average, undergrads spend 8-12 hours/week during the school year and 40-45 hrs/wk over the summer.
Suggested Experience:This group is highly interdiscplinary. It includes physical, organic, and inorganic chemists as well as physicists.  Chemistry through P-Chem and Physics through 202 are suggested.

Description: Organic synthesis related to nanoscale science.  Construction of molecular computers, nanotrucks, etc.

Your Job in the Lab: The students are given a project along side a grad student or post doc to work on.

Recommended experience: The students must have taken organic chemistry (CHEM 211-212) and have done very well in the class.

Positions Open: There are currently 1-2 positions open for the summer and fall of 2000.

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R. Bruce Weisman

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What you would do: Projects involve photophysical studies of fullerenes and their derivatives. Typical activities include sample purification followed by the measurement of triplet decay kinetics and transient spectra.  The goals are to investigate triplet state properties and deactivation channels such as energy transfer and self-quenching.  The apparatus is functional and easy to use, allowing undergraduates to obtain real results even when their lab time is limited.
What you would learn: This is a good chance to take a small project to completion and be a co-author on publications.  Students also have opportunities to present the work at local meetings
Environment:Undergrads work with graduate students, but are closely supervised by the professor.
Suggested Experience: Should have completed or be taking the Physical Chemstry sequence.

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Kenton H. Whitmire

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Description: The Whitmire research group is involved in a number of inorganic and organometallic research projects.  These projects involve synthesis of new cluster compounds, metal alkoxides and other metal complexes which are targeted for their relevance to catalysis, materials science and pharmaceuticals.  We are exploring the catalysis of industrially important transformations of organic molecules as catalyzed by transition metal clusters and have a new apparatus that allows us to probe these reactions directly under reaction conditions.  We are also interested in preparing new metal alkoxides and are developing routes to making heterometallic species which may be used as precursors to existing or new solid state materials or oxidation catalysts.  We are also beginning to develop a program in pharmaceutical bismuth compounds since bismuth has a documented biological activity but is the least toxic of the heavy metals.  These synthetic studies are under girded by molecular orbital calculations and we collaborate with the research group of Professor Jean-Yves Saillard in Rennes, France, in order to carry out that work.  Besides the normal synthetic and analytical techniques taught in the laboratory classes at Rice, members of the group learn hands on about single crystal x-ray diffraction and multinuclear, variable temperature nuclear magnetic resonance which are very valuable for understanding the structures in both solid and solution phases as well as probing molecular dynamics.

Your Job in the Lab: Undergraduates who join the research group are given independent research projects and are encouraged to develop their own ideas and strategies in consultation with Professor Whitmire and the other researchers in the group.  Research plans are developed after consideration of the undergraduate student's goals and interests in research and what types of techniques he/she wishes to learn.

Recommended experience: Generally having a solid background in freshman chemistry is adequate. Much of the lab work is specialized, such as the use of vacuum lines, Schlenk lines and dry boxes,  and is taught during the course of the project.

Positions Open: I have at least one and probably two paid positions available for the summer 2000 and could easily accommodate 4 students during the fall semester.

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Lon J. Wilson

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Organization: The graduate students are very helpful, and the professor comes by once a day, but is generally less accessible.
Environment: This is a fun group, with some of the more cheerful grad students in the university. They sing along with songs on the radio, have a sense of humor, and usually seem to enjoy what they're doing. Typically, you'll spend 10-12 hrs/wk in lab, doing a lot of repetitive chromatography.
What you would learn:New challenges are always presenting themselves.
Suggested Experience:Definitely Chem 351/352. Previous lab experience is helpful, since you're on your own more in this lab than in others. There aren't people around to show you basic techniques, like how to set up a distillation apparatus.
 

Last Modified on Saturday, February 15, 2003 01:48 PM

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