| Week |
Dates |
Topic |
Chapter |
| 1 |
1/13/04
1/15/04 |
Overview of Course
Introduction to pharmaceutical engineering |
1 |
| 2 |
1/20/04
1/22/04 |
Physiological issues involved in drug therapy
Introduction to Pharmacokinetics |
2
3 |
| 3 |
1/27/04
1/28/04 |
Pharmacokinetic Modeling: Absorption, Distribution, Metabolism, and Elimination Kinetics
IV bolus dose
Case study I |
3 |
| 4 |
2/3/04
2/5/04 |
Bioavailability, clearance, repetitive dosing
Homework 1 due (IV dosing, AUC, elimination)
Case study II |
3 |
| 5 |
2/10/04
2/12/04 |
Membrane transport of orally delivered drugs
Factors influencing drug absorption and availability
Homework 2 due (bioavailability, clearance, repetitive dosing)
Case study III |
4 |
| 6 |
2/17/04
2/19/04 |
Effect of route of delivery on drug action
Chemical kinetics and drug stability
Homework 3 due (pKas, metabolism, drug interactions)
Case study IV |
5
6 |
| 7 |
2/24/04
2/26/04 |
Introduction to Pharmaceutics
Preformulation & delivery systems |
7 |
| 8 |
3/1/04
3/3/04 |
SPRING BREAK |
|
| 9 |
3/9/04
3/11/04 |
Topical and Transdermal drug delivery
Disperse systems
Homework 4 due (chemical kinetics) |
8
9 |
| 10 |
3/16/04
3/18/04 |
Solid dosage forms: Tablets
Capsules
Homework 5 due (review) |
10
11 |
| 11 |
3/23/04
3/25/04 |
Parenteral delivery
Pulmonary drug delivery |
12
14 |
| 12 |
3/30/04
4/1/04 |
Controlled release drug delivery |
15 |
| 13 |
4/6/04
4/8/04 |
Targeted delivery
Homework 6 due (controlled drug delivery) |
16 |
| 14 |
4/13/04
4/15/04 |
Biotechnology based therapies |
22 |
| 15 |
4/20/04
4/22/04 |
Anti-cancer chemotherapies
Regulatory issues |
19 |
