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2014

K.M. Hubka, R.L. Dahlin, V.V. Meretoja, F.K. Kasper, and A.G. Mikos, “Enhancing Chondrogenic Phenotype for Cartilage Tissue Engineering: Monoculture and Coculture of Articular Chondrocytes and Mesenchymal Stem Cells,” Tissue Eng. Part B: Reviews, 20, 641-654 (2014).

S.-E. Lamhamedi-Cherradi, M. Santoro, V. Ramammoorthy, B.A. Menegaz, G. Bartholomeusz, L.R. Iles, H.M. Amin, A.J. Livingston, A.G. Mikos, and J.A. Ludwig, “3D Tissue-Engineered Model of Ewing’s Sarcoma,” Adv. Drug Deliv. Rev., 79-80, 155-171 (2014).

A.M. Tatara, M.E. Wong, and A.G. Mikos, “In Vivo Bioreactors for Mandibular Reconstruction,” J. Dent. Res., 93, 1196-1202 (2014).

R.L. Dahlin, V.V. Meretoja, M. Ni, F.K. Kasper, and A.G. Mikos, “Chondrogenic Phenotype of Articular Chondrocytes in Monoculture and Co-Culture with Mesenchymal Stem Cells in Flow Perfusion,” Tissue Eng. Part A, 20, 2883-2891 (2014).

S.R. Shah, A.M. Henslee, P.P. Spicer, S. Yokota, S. Petrichenko, S. Allahabadi, G.N. Bennett, M.E. Wong, F.K. Kasper, and A.G. Mikos, “Effects of Antibiotic Physicochemical Properties on their Release Kinetics from Biodegradable Polymer Microparticles,” Pharm. Res., 31, 3379-3389 (2014).

A.W.G. Nijhuis, S. Takemoto, M.R. Nejadnik, Y. Li, X. Yang, D.A. Ossipov, J. Hilborn, A.G. Mikos, M. Yoshinari, J.A. Jansen, and S.C.G. Leeuwenburgh, “Rapid Screening of Mineralization Capacity of Biomaterials by Means of Quantification of Enzymatically Deposited Calcium Phosphate,” Tissue Eng. Part C: Methods, 20, 838-850 (2014).

J.E. Trachtenberg, P.M. Mountziaris, J.S. Miller, M. Wettergreen, F.K. Kasper, and A.G. Mikos, “Open-Source Three-Dimensional Printing of Biodegradable Polymer Scaffolds for Tissue Engineering,” J. Biomed. Mater. Res. Part A, 102A, 4326-4335 (2014).

L.A. Kinard, R.L. Dahlin, J. Lam, S. Lu, E.J. Lee, F.K. Kasper, and A.G. Mikos, “Synthetic Biodegradable Hydrogel Delivery of Demineralized Bone Matrix for Bone Augmentation in a Rat Model,” Acta Biomaterialia, 10, 4574-4582 (2014).

C.J. Needham, S.R. Shah, R.L. Dahlin, L.A. Kinard, J. Lam, B.M. Watson, S. Lu, F.K. Kasper, and A.G. Mikos, “Osteochondral Tissue Regeneration Through Polymeric Delivery of DNA Encoding for the SOX Trio and RUNX2,” Acta Biomaterialia, 10, 4103-4112 (2014).

S. Lu, J. Lam, J.E. Trachtenberg, E.J. Lee, H. Seyednejad, J.J.J.P. van den Beucken, Y. Tabata, M.E. Wong, J.A. Jansen, A.G. Mikos, and F.K. Kasper, “Dual Growth Factor Delivery from Bilayered, Biodegradable Hydrogel Composites for Spatially-Guided Osteochondral Tissue Repair,” Biomaterials, 35, 8829-8839 (2014).

J. Lam, S. Lu, E.J. Lee, J.E. Trachtenberg, V.V. Meretoja, R.L. Dahlin, J.J.J.P. van den Beucken, Y. Tabata, M.E. Wong, J.A. Jansen, A.G. Mikos, and F.K. Kasper, “Osteochondral Defect Repair Using Bilayered Hydrogels Encapsulating Both Chondrogenically and Osteogenically Pre-Differentiated Mesenchymal Stem Cells in a Rabbit Model,” Osteoarthritis Cartilage, 22, 1291-1300 (2014).

J. Lam, K. Kim, S. Lu, Y. Tabata, D.W. Scott, A.G. Mikos, and F.K. Kasper, “A Factorial Analysis of the Combined Effects of Hydrogel Fabrication Parameters on the In Vitro Swelling and Degradation of Oligo(Poly(Ethylene Glycol) Fumarate) Hydrogels,” J. Biomed. Mater. Res. Part A, 102A, 3477-3487 (2014).

M. Santoro, A.M. Tatara, and A.G. Mikos, “Gelatin Carriers for Drug and Cell Delivery in Tissue Engineering,” J. Controlled Release, 190, 210-218 (2014).

E.L.S. Fong, M. Martinez, J. Yang, A.G. Mikos, N.M. Navone, D.A. Harrington, and M.C. Farach-Carson, “Hydrogel-Based 3D Model of Patient-Derived Prostate Xenograft Tumors Suitable for Drug Screening,” Mol. Pharm., 11, 2040-2050 (2014).

R.L. Dahlin, J.G. Gershovich, F.K. Kasper, and A.G. Mikos, “Flow Perfusion Co-Culture of Human Mesenchymal Stem Cells and Endothelial Cells on Biodegradable Polymer Scaffolds,” Ann. Biomed. Eng., 42, 1381-1390 (2014).

R.L. Dahlin, L.A. Kinard, J. Lam, C.J. Needham, S. Lu, F.K. Kasper, and A.G. Mikos, “Articular Chondrocytes and Mesenchymal Stem Cells Seeded on Biodegradable Scaffolds for the Repair of Cartilage in a Rat Osteochondral Defect Model,” Biomaterials, 35, 7460-7469 (2014).

B.M. Watson, F.K. Kasper, P.S. Engel, and A.G. Mikos, “Synthesis and Characterization of Injectable, Biodegradable, Phosphate-Containing, Chemically Cross-Linkable, Thermoresponsive Macromers for Bone Tissue Engineering,” Biomacromolecules, 15, 1788-1796 (2014).

L.A. Kinard, R.L. Dahlin, A.M. Henslee, P.P. Spicer, C.-Y. Chu, Y. Tabata, J.J.J.P. van den Beucken, J.A. Jansen, S. Young, M.E. Wong, F.K. Kasper, and A.G. Mikos, “Tissue Response to Composite Hydrogels for Vertical Bone Augmentation in the Rat,” J. Biomed. Mater. Res. Part A, 102A, 2079-2088 (2014).

V.V. Meretoja, R.L. Dahlin, S. Wright, F.K. Kasper, and A.G. Mikos, “Articular Chondrocyte Redifferentiation in 3D Co-Cultures with Mesenchymal Stem Cells,” Tissue Eng. Part C: Methods, 20, 514-523 (2014).

T.N. Vo, J.E. Trachtenberg, and A.G. Mikos, “In Vitro Techniques for Biomaterial Evaluation in Bone and Cartilage Tissue Engineering,” Regener. Med., J. Japan. Soc. Regener. Med., 13, 125-149 (2014).

A.M. Henslee, P.P. Spicer, S.R. Shah, A.M. Tatara, F.K. Kasper, A.G. Mikos, and M.E. Wong, “Use of Porous Space Maintainers in Staged Mandibular Reconstruction,” Oral Maxillofac. Surg. Clin. North Am., 26, 143-149 (2014).

E.J. Levorson, P.M. Mountziaris, O. Hu, F.K. Kasper, and A.G. Mikos, “Cell-Derived Polymer/Extracellular Matrix Composite Scaffolds for Cartilage Regeneration, Part 1: Investigation of Cocultures and Seeding Densities for Improved Extracellular Matrix Deposition,” Tissue Eng. Part C: Methods, 20, 340-357 (2014).

E.J. Levorson, O. Hu, P.M. Mountziaris, F.K. Kasper, and A.G. Mikos, “Cell-Derived Polymer/Extracellular Matrix Composite Scaffolds for Cartilage Regeneration, Part 2: Construct Devitalization and Determination of Chondroinductive Capacity,” Tissue Eng. Part C: Methods, 20, 358-372 (2014).

E.J. Levorson, M. Santoro, F.K. Kasper, and A.G. Mikos, “Direct and Indirect Co-Culture of Chondrocytes and Mesenchymal Stem Cells for the Generation of Polymer/Extracellular Matrix Hybrid Constructs,” Acta Biomaterialia, 10, 1824-1835 (2014).

S.N. Tzouanas, A.K. Ekenseair, F.K. Kasper, and A.G. Mikos, “Mesenchymal Stem Cell and Gelatin Microparticle Encapsulation in Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering,” J. Biomed. Mater. Res. Part A, 102A, 1222-1230 (2014).

B.M. Watson, F.K. Kasper, and A.G. Mikos, “Phosphorous-Containing Polymers for Regenerative Medicine,” Biomed. Mater., 9, 025014 (10pp) (2014).

E.J. Lee, F.K. Kasper, and A.G. Mikos, “Biomaterials for Tissue Engineering,” Ann. Biomed. Eng., 42, 323-337 (2014).

J. Ma, F. Yang, S.K. Both, M. Kersten-Niessen, M. Bongio, J. Pan, F.-Z. Cui, F.K. Kasper, A.G. Mikos, J.A. Jansen, and J.J.J.P. van den Beucken, “Comparison of Cell-Loading Methods in Hydrogel Systems,” J. Biomed. Mater. Res. Part A, 102A, 935-946 (2014).

E.J. Lee, J.J. Tabor, and A.G. Mikos, “Leveraging Synthetic Biology for Tissue Engineering Applications,” Inflamm. Regener., 34, 15-22 (2014).

J. Lam, S. Lu, Y. Tabata, A.G. Mikos, and F.K. Kasper, "Generation of Osteochondral Tissue Constructs with Chondrogenically and Osteogenically Pre-differentiated Mesenchymal Stem Cells Encapsulated in Bilayered Hydrogels," Acta Biomaterialia, 10, 1112-1123 (2014).

T.N. Vo, A.K. Ekenseair, F.K. Kasper, and A.G. Mikos, “Synthesis, Physicochemical Characterization, and Cytocompatibility of Bioresorbable, Dual-Gelling Injectable Hydrogels,” Biomacromolecules, 15, 132-142 (2014).

E.L. Fong, M. Santoro, M.C. Farach-Carson, F.K. Kasper, and A.G. Mikos, “Tissue Engineering Perfusable Cancer Models,” Curr. Opin. Chem. Eng., 3, 112-117 (2014).

C.G. Ambrose, T.A. Clyburn, J. Mika, G.R. Gogola, H.B. Kaplan, A. Wanger, and A.G. Mikos, “Evaluation of Antibiotic-Impregnated Microspheres for the Prevention of Implant-Associated Orthopaedic Infections,” J. Bone Joint Surg., 96, 128-134 (2014).

C.J. Needham, S.R. Shah, P.M. Mountziaris, F.K. Kasper, and A.G. Mikos, “Modulation of Polyplex Release from Biodegradable Microparticles through Poly(Ethylenimine) Modification and Varying Loading Concentration,” Pharm. Res., 31, 77-85 (2014).

R.L. Dahlin, M. Ni, V.V. Meretoja, F.K. Kasper, and A.G. Mikos, “TGF-ß3-Induced Chondrogenesis in Co-Cultures of Chondrocytes and Mesenchymal Stem Cells on Biodegradable Scaffolds,” Biomaterials, 35, 123-132 (2014).