Publications

B. K. Zolman, M. Monroe-Augustus, B. Thompson, J.W. Hawes, K. A. Krukenberg, S. P. T. Matsuda and B. Bartel, " chy1, an Arabidopsis mutant with impaired ß-oxidation, is defective in a peroxisomal ß-hydroxyisobutyryl-CoA hydrolase," 2001, J. Biol. Chem., 276, 31037-31046.

H. G. Schepmann, J. Pang and S. P. T. Matsuda, "Cloning and characterization of Ginkgo biloba levoprimaradiene synthase, which catalyzes the first committed stp in ginkgolide biosynthesis", 2001, Arch. Biochem. Biophys. 392, 263-269

B. M. Joubert, F.S. Buckner, and S. P. T. Matsuda, "Trypanosome and animal lanosterol synthases use different catalytic motifs," 2001, Org. Lett., 3, 1957-1960.

R. G. Gardner, H. Shan, S. P. T. Matsuda, and R. Y. Hampton, "A positive oxysterol-derived signal for 3-hydroxy-3-methylglutaryl CoA reductase degradation in yeast," 2001, J. Biol. Chem. 276, 8681-8694.

M.M. Meyer, M.J.R. Segura, W.K.Wilson, and S.P.T. Matsuda, "Oxidosqualene cyclase residues that promote formation of cycloartenol, lanosterol, and parkeol," Angew. Chem, 2000, 39, 4090-4092.

S. P. T. Matsuda, L. B. Darr, E. A. Hart, J. B. R. Herrera, K. E. McCann, M. M. Meyer, J. Pang, H. G. Schepmann, and W. K. Wilson. "Steric bulk at cycloartenol synthase position 481 influences cyclization and deprotonation". Org. Lett. 2000, 2, 2261-2263.

F. S. Buckner L. N. Ngyuen B. M. Joubert S. P. T. Matsuda, "Cloning and heterologous expression of the Trypanosoma brucei lanosterol synthase gene," Mol. Biochem. Parasitol., 2000, 110, 399-403.

M. J. R. Segura, M. M. Meyer, and S. P. T. Matsuda. "Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol". Org. Lett 2000, 2, 2257-2259.

J. B. R. Herrera, W. K. Wilson, and S. P. T. Matsuda. "A tyrosine to threonine mutation converts cycloartenol synthase to an oxidosqualene cyclase that forms lanosterol as its major product". J. Am. Chem. Soc. 2000 122, 6765-6766.

M. A. Lovato, E. A. Hart, M. J. R. Segura, J.-L. Giner, and S. P. T. Matsuda. "Functional cloning of an Arabidopsis thaliana cDNA encoding cycloeucalenol cycloisomerase". J. Biol. Chem. 2000, 275, 13394-13397.

S. M. Godzina*, M. A. Lovato*, M. M. Meyer, K. A. Foster, W. K. Wilson, W. Gu, E. L. de Hostos, and S. P. T. Matsuda. "Cloning and characterization of the Dictyostelium discoideum cycloartenol synthase cDNA". Lipids 2000, 36, 249-255.

B. M. Joubert, L. Hua, and S. P. T. Matsuda. "Steric bulk at position 454 in Saccharomyces cerevisiae lanosterol synthase influences B-ring formation but not deprotonation". Org. Lett. 2000, 2, 339-341.

E. Roessler, L. Mitaz, Y. Z. Du, H. S. Scott, J. Chang, C. Rossier, M. Guipponi, S. P. T. Matsuda, M. Muenke, and S. E. Antonarakis. "Structure of the human lanosterol synthase gene and its analysis as a candidate for holoprosencephaly (HPE1)". Human Genet. 1999, 105, 489-495.

E. A. Hart, L. Hua, L. A. Darr, W. K. Wilson, J. Pang, and S. P. T. Matsuda. "Directed evolution to investigate steric control of enzymatic oxidosqualene cyclization. An isoleucine to valine mutation in cycloartenol synthase allows lanosterol and parkeol biosynthesis". J. Am. Chem. Soc. 1999, 121, 9887-9888.

L. B. Darr, S. M. Godzina, and S. P. T. Matsuda. "A rice cDNA (AF169966) similar to cycloartenol synthase". Plant Physiol. 1999, 121, 686.

L. Hua and S. P. T. Matsuda. "The molecular cloning of 8-epicedrol synthase from Artemisia annua". Arch. Biochem. Biophys. 1999, 369, 208-212.

J. B. R. Herrera and B. Bartel and W. K. Wilson and S. P. T. Matsuda. "Cloning and characterization of the Arabidopsis thaliana lupeol synthase gene". Phytochemistry 1998, 49, 1905-1911.

S. P. T. Matsuda "On the Diversity of Oxidosqualene Cyclases" in Biochemical Principles and Mechanisms of Biosynthesis and Biodegradation of Polymers. Steinbüchel, A., Ed.; Wiley-VCH: Weinheim, 1998, pp 300-307.

E. J. Corey, H. Cheng, C. H. Baker, S. P. T. Matsuda, D. Li, and X. Song. "Studies on the substrate binding segments and catalytic action of lanosterol synthase. Affinity labeling with carbocations derived from mechanism-based analogs of 2,3-oxidosqualene and site-directed mutagenesis probes". J. Am. Chem. Soc. 1997, 119, 1289-1296.

E. J. Corey, H. Cheng, C. H. Baker, S. P. T. Matsuda, D. Li, and X. Song. "Methodology for the preparation of pure recombinant S. cerevisiae lanosterol synthase using a baculovirus expression system. Evidence that oxirane cleavage and A-ring formation are concerted in the biosynthesis of lanosterol from 2,3-oxidosqualene". J. Am. Chem. Soc. 1997, 119, 1277-1288.

E. J. Corey, S. P. T. Matsuda, C. H. Baker, A. Y. Ting, and H. Cheng. "Molecular cloning of a Schizosaccharomyces pombe cDNA encoding lanosterol synthase and investigation of conserved tryptophan residues". Biochem. Biophys. Res. Commun. 1996, 219, 327-331.

E. J. Corey, S. C. Virgil, H. Cheng, C. H. Baker, S. P. T. Matsuda, V. Singh, and S. Sarshar. "New insights regarding the cyclization pathway for sterol biosynthesis from (S)-2,3-oxidosqualene". J. Am. Chem. Soc. 1995, 117, 11819-11820.

C. H. Baker, S. P. T. Matsuda, D. R. Liu, and E. J. Corey. "Molecular cloning of the human gene encoding lanosterol synthase from a liver cDNA library". Biochem. Biophys. Res. Commun. 1995, 213, 154-160.

E. J. Corey, S. P. T. Matsuda, and B. Bartel. "Molecular cloning, characterization, and overexpression of ERG7, the Saccharomyces cerevisiae gene encoding lanosterol synthase". Proc. Natl. Acad. Sci. USA 1994, 91, 2211-2115.

E. J. Corey, S. P. T. Matsuda, and B. Bartel. "Isolation of an Arabidopsis thaliana gene encoding cycloartenol synthase by functional expression in a yeast mutant lacking lanosterol synthase by the use of a chromatographic screen". Proc. Natl. Acad. Sci. USA 1993, 90, 11628-11632.

E. J. Corey, K. Y. Yi, and S. P. T. Matsuda. "Catalytic enantioselective synthesis of 3(S)-2,3-oxidosqualene". Tetrahedron Lett. 1992, 33, 2319-2322.

E. J. Corey and S. P. T. Matsuda. "Purification of the 2,3-oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae". J. Am. Chem. Soc. 1991, 113, 8172-8174.

E. J. Corey, S. W. Wright, and S. P. T. Matsuda. "Stereochemistry and mechanism of the biosynthesis of leukotriene A4 from 5(S)-hydroperoxy-6(E),8,11,14(Z)-eicosatetraenoic acid. Evidence for an organoiron intermediate". J. Am. Chem. Soc. 1989, 111, 1452-1455.

E. J. Corey, S. P. T. Matsuda, R. Nagata, and M. B. Cleaver. "Biosynthesis of 8-(R)-HPETE and preclavulone A from arachidonate in several species of Caribbean coral. A widespread route to marine prostanoids". Tetrahedron Lett. 1988, 29, 2555-2558.

E. J. Corey and S. P. T. Matsuda. "Generality of marine prostanoid biosynthesis by the 2-oxidopentadienyl cation pathway". Tetrahedron Lett. 1987, 28, 4247-4250.

E. J. Corey, M. d'Alarcao, S. P. T. Matsuda, P. T. Lansbury Jr., and Y. Yamada. "Intermediacy of 8-(R)-HPETE in the conversion of arachidonic acid to pre-clavulone A by Clavularia viridis. Implications for the biosynthesis of marine prostanoids". J. Am. Chem. Soc. 1987, 109, 289-290.

P. Uotila, C. Cunard, R. Vargas, M. d'Alarcao, S. Matsuda, E. J. Corey, and P. W. Ramwell. "Involvement of icosanoids in endothelium-derived relaxing factor". Adv. Prost. Thromb. Leuk. Res. 1987, 17, 1103-1107.

P. Uotila, R. Vargas, B. Wroblewska, M. d'Alarcao, S. P. Matsuda, E. J. Corey, C. M. Cunard, and P. W. Ramwell. "Relaxing effects of 15-lipoxygenase products of arachidonic acid on rat aorta". J. Pharmacol. Exp. Ther. 1987, 242, 945-949.

E. J. Corey, M. d'Alarcao, and S. P. T. Matsuda. "A new irreversible inhibitor of soybean lipoxygenase; relevance to mechanism". Tetrahedron Lett. 1986, 27, 3585-3588.