Peptide Orientation






H. W. Huang and Y. Wu, "Lipid-Alamethicin Interactions Influence Alamethicin Orientation." Biophys. J. 60, 1079-1087 (1991).

S. J. Ludtke, K. He, Y. Wu, and H. W. Huang, “Cooperative Membrane Insertion of Magainin Correlated with Its Cytolytic Activity” Biochim. Biophys. Acta  1190, 181-184 (1994)


W. T. Heller, K. He, S. J. Ludtke, T. A. Harroun, and H. W. Huang, "Effect of changing the size of lipid headgroup on peptide insertion into membrane," Biophys. J. 73: 239-244 (1997)

W. T. Heller, A. J. Waring, R. I. Lehrer, H. W. Huang, “Multiple states of beta-sheet peptide protegrin in lipid bilayers,” Biochemistry  37: 17331-17338 (1998)

L. Yang, T. A. Harroun, T.  M. Weiss, L. Ding and H. W. Huang, “Barrel-stave Model or Toroidal Model? A Case Study on Melittin Pores,” Biophys. J. 81: 1475-1485 (2001)

T. M. Weiss, L. Yang, L. Ding, A. J. Waring, R. I. Lehrer, and H. W. Huang, “Two states of cyclic antimicrobial peptide RTD-1 in lipid bilayers” Biochemistry 41: 10070-10076 (2002)

F. Y. Chen, M. T. Lee and H. W. Huang, “Sigmoidal concentration dependence of antimicrobial peptide activities: a case study on alamethicin,” Biophys. J. 82: 908-914 (2002).

F. Y. Chen, M. T. Lee and H. W. Huang, “Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation,” Biophys. J. 84: 3751-3758 (2003)

M. T. Lee, F. Y. Chen and H. W. Huang, "Energetics of pore formation induced by antimicrobial peptides" Biochemistry 43: 3590-3599 (2004).