Research Interests
Dictyostelium
Selected Publications (click on title to view PDF)
- Gao T, Roisin-Bouffay C, Hatton RD, Tang L, Brock DA, DeShazo T, Olson L, Hong WP, Jang W, Canseco E, Bakthavatsalam D, Gomer RH. 2007. A cell number-counting factor regulates levels of a novel protein, SslA, as part of a group size regulation mechanism in Dictyostelium. Eukaryotic Cell. 6(9):1538-51
- Brock DA, van Egmond WN, Shamoo Y, Hatton RD, Gomer RH. 2006. A 60-kilodalton protein component of the counting factor complex regulates group size in Dictyostelium discoideum. Eukaryotic Cell. 5(9):1532-8.
- Brock, DA and Gomer, RH. 2005. A secreted factor represses cell proliferation in Dictyostelium. Development 132(20):4553-4562.
- Brock DA, Ehrenman K, Ammann R, Tang Y, and Gomer, RH. 2003. Two components of a secreted cell number-counting factor bind to cells and have opposing effects on cAMP signal transduction in Dictyostelium. J Biol Chem. 278(52):52262-52272.
- Brock DA, Hatton RD, Giurgiutiu DV, Scott B, Jang W, Ammann R, and Gomer RH. 2003. CF45-1, a secreted protein which participates in Dictyostelium group size regulation.Eukaryotic Cell. 2(4):788-97.
- Brock DA, Hatton RD, Giurgiutiu DV, Scott B, Ammann R, Gomer RH. 2002. The different components of a multisubunit cell number-counting factor have both unique and overlapping functions. Development. 129(15):3657-3668.
- Brock, DA and Gomer, RH. 1999. A cell-counting factor regulating structure size in Dictyostelium. Genes Dev. 13(15):1960-1969.
- Brock DA, Buczynski G, Spann TP, Wood SA, Cardelli J, Gomer RH. 1996. A Dictystelium mutant with defective aggregate size determination. Development. 122(9):2569-2578.
- Spann TP, Brock DA, Lindsey DF, Wood SA, Gomer RH. 1996. Mutagenesis and gene identification in Dictyostelium by shotgun antisense. Proc Natl Acad Sci U S A. 93(10):5003-5007.