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Seminars
Thermodynamic and Kinectic Origins of Alzheimer's and Related Dieseases: A Chemical Engineer's Perspective
Professor Carol Hall
Camille Dreyfus Distinguished University Professor
Department of Chemical and Biomolecular Engineering
North Carolina State University
When: Thursday, March 29, 2007
Time: 4:00 p.m.
Where: 301 Sewall Hall
Abstract:
The pathological hallmark of more than twenty neurodegenerative diseases, like Alzheimer's, Parkinson's and the prion diseases, is the presence within the brain of plaques containing ordered protein aggregates called fibrils. It is not yet known why these structures form in some individuals and not in others, or whether the plaques are toxic or Nature's way of sequestering toxic species. Dr. Hall will describe current thinking on the scientific underpinnings for this phenomenon, and her computational efforts to contribute to our knowledge of how and why proteins assemble into fibrils.
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