Computational and Experimental

Biomechanics Laboratory

Brandon Bucklen, Ph.D. Candidate

Interests:

Brandon Bucklen is a Ph.D. Candidate in the Department of Bioengineering at Rice University, Houston, TX. He received his B.S. degree in Mechanical Engineering from Georgia Tech, Atlanta, GA. His current research interests are in computational biology with special focus on tissue engineering and the mechanobiology of hard connective tissue. The title of my thesis is:

" Investigation of Surface Mechanical Environment as an Optimization Criterion for Improved Tissue Engineering Scaffolds"

 

Publications:

Book Chapters:

1.     Bucklen B., Wettergreen M., Liebschner M.: "Mechanical Aspects of Tissue Engineering". In Seminars in Plastic Surgery/Publisher Thieme on the topic of "Tissue Repair, Regeneration and Engineering in Plastic Surgery". Editors: Dr. C. Randall Harrell/Dr. Saleh M. Shenaq/Dr. Eser Yuksel. Volume 19, Number 3, 261-270,2005.

2.     Wettergreen M., Bucklen B., Liebschner M.: "CAD assembly process for bone replacement scaffold in Computer-Aided Tissue Engineering". In Virtual & Rapid Prototyping in Medicine, Part II - Bio-Manufacturing. Editors: Bidanda B. and Bˆ°rtolo P. Springer. In Press

 

Peer Reviewed Publications:

1.     Bucklen B., Wettergreen M., Heinkenschloss M., Liebschner M.: "Surface-Based Scaffold Design: A Mechanobiological Approach." IMECE 2005, Advances in Bio-Manufacturing. IMECE2005-81985.

2.     Wettergreen M., Bucklen  G., Sun W., Liebschner M.: "Computer-Aided Tissue Engineering in Whole Bone Replacement Treatment". IMECE 2005, Advances in Bio-Manufacturing. IMECE2005-82000.

3.     Wettergreen M., Bucklen B., Starly B., Yuksel E., Sun W., Liebschner M.: "Unit Block Library of Basic Architectures for use in Computer-aided Tissue Engineering of Bone Replacement Scaffolds". IMECE 2005, Advances in Bio-Manufacturing. IMECE2005-81984.

4.     Wettergreen M., Bucklen B., Templeton A. Sun W., Liebschner M.: "Computer Aided Tissue Engineering of Human Vertebral Body." Annals of Biomedical Engineering, 33(10): 1333-1343, 2005.

5.     Wettergreen M., Bucklen B., Starly B., Yuksel E., Sun W., Liebschner M.: "Creation of a Unit Block Library of Architectures for Use in Assembled Scaffold Engineering." Computer-Aided Design, Special Issue: Bio-CAD, 37(11): 1141-49, 2005.

6.     Liebschner M., Mueller R., Rajapakse C., Bucklen B., Wimalawansa S., Gunaratne G.: "Testing Two Predictions for Fracture Load Using Computer Models of Trabecular bone."  Biophysical Journal, 89, 1-9, 2005.

Submitted and in Preparation

7.  Bucklen B., Wettergreen M., Yuksel E., Liebschner M.: "Bone derived CAD library for the assembly of scaffolds in Computer-Aided Tissue Engineering." Acta Biomaterialia, Submitted.

8.  Bucklen B., Wettergreen M., Liebschner M.: " What is the Driving Force Behind Mechanical Adaptation of Trabecular Bone? : A Parametric Finite Element Study." Bone, Submitted.

9.  Wettergreen M., Bucklen B., Mikos A., Liebschner M.: ’ÄúStructural Properties of Regular Architectures, Part 1: Geometric Characterization and Finite Element Structural Comparison of Platonic and Archimedian Solids’Äù. In Preparation.

10.  Liebschner M., Mistry A., Bucklen B., Boriek A.: "Mirosin Deficiency Leads to Alteration in the Mechanical Properties and Structure of the Femur." Journal of Applied Physiology. In Preparation.

 

Conference Presentations:

1.         Bucklen B., Wettergreen M., Liebschner M.: "Driving Force Behind Mechanical Adaptation of Trabecular Bone Tissue: A Parametric FEA Study". 2006 Annual Fall Meeting Biomedical Engineering Society, October 11-14, Chicago, IL, 2006.

2.          Wettergreen M., Bucklen B., Liebschner M.: " Assembly of Trabecular Bone Derived Scaffold Micro-Architectural for Patient Specific Applications". 2006 Annual Fall Meeting Biomedical Engineering Society, October 11-14, Chicago, IL, 2006.

3.         Wettergreen M., Bucklen B., Liebschner M., Wei S.: "Design and Characterization of Cellular Solids from Modeling through Solid Freeform Fabrication". 17th Solid Freeform Fabrication Symposium, Austin, Texas, 14-16 August, 2006.

4.         Bucklen B., Wettergreen M., Heinkenschloss M., Liebschner M.: "Surface-Based Scaffold Design: A Mechanobiological Approach."  Advances in Bio-Manufacturing, ASME  IMECE 2005, Orlando, FL, November 5-11, 2005.

5.         Wettergreen M., Bucklen B., Sun W., Liebschner M.: "Computer-Aided Tissue Engineering in Whole Bone Replacement Treatment." Advances in Bio-Manufacturing, ASME  IMECE 2005, Orlando, FL, November 5-11, 2005.

6.         Wettergreen M., Bucklen B., Starly B., Yuksel E., Sun W., Liebschner M.: "Unit Block Library of Basic Architectures for Use in Computer-Aided Tissue Engineering of Bone Replacement Scaffolds." Advances in Bio-Manufacturing, ASME  IMECE 2005, Orlando, FL, November 5-11, 2005.

7.         Wettergreen M., Bucklen B., Mikos A.G., Liebschner M.: "Tailoring the Mechanical Environment of Scaffolds with Computer Aided Design and Rapid Prototyping." 2004 Annual Fall Meeting Biomedical Engineering Society, October 13-16, Philadelphia, PA, 2004.

8.         Wettergreen M., Bucklen B., Mikos A., Liebschner M.: " Scaffold Design Using Model-Based Mechanotransduction Principles." 2003 Annual Fall Meeting Biomedical Engineering Society, October 1-4, Nashville, TN, 2003.

9.         Wettergreen M., Bucklen B., Mikos A., Liebschner M.: ’ÄúScaffold Optization for Load-Bearing Applications in Orthopaedics.’Äù 20st Annual Houston Conference on Biomedical Engineering Research, HSEMB 2003, April 3-4, Houston, TX, 2003.

 

 

 

 

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